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Mammalian hearts have almost no ability to grow new heart muscle cells, called cardiomyocytes, after birth. Thus, dead tissue after an adult heart attack is not repaired with new cardiomyocytes. It is instead replaced with scar tissue that weakens the pumping power of the heart and often leads to heart failure. One promising strategy to remuscularize the injured heart is the direct cardiac reprogramming of heart fibroblast cells into cardiomyocytes. In apaperpublished in Circ nike dunk low ulation,University of Alabama at Birminghamresearchers Yang Zhou, Ph.D., and Rui Lu, Ph.D., have identified TBX20 as the key missing transcription factor in existing cocktails for direct cardiac reprogramming of human fibroblasts. Adding TBX20 to the reprogramming cocktail MGT 133, they report, promoted cardiac reprograming and activated genes associated with cardiac contractility, maturation an asics gel kayano d a vent claquette yeezy ricular location of the heart muscle cell. Mechanistically, they found that TBX20 synergistically colocalizes with KARACHI:By now it has become a near-certainty that if a PML-N leader says 鈥榯he sky is up鈥? PTI chief Imran Khan will say it is down. And then he will threaten to stage a sit-in.Imran鈥檚 most recent 鈥榗ounter-argument鈥? however, may be a bridge too far even for his supporters, as the erstwhile Pakistan cricket team captain made critical, and arguably racist comments, about the international players t adidas samba uomo hat participated in the Pakistan Super League final in Lahore.In what seems to be footage from an internal party meeting, Imran brands the international players who came for the match 鈥榩hateechar鈥?(shabby).Imran Khan in eye of storm over 'vile' comments about foreign PSL players鈥淚 don鈥檛 even know the name of any of these so-called foreign players鈥hey just picked up players from wherever鈥ome random players so-c adidas campus 00's alled foreign players鈥hey just picked up players from wherever鈥ome random players from Africa and called them foreign players,鈥?Imran said, before adding that such players would h adidas samba vegan ave